If there is pain in the small stomach after vaginal insertion of nifurtimox, it is possible that during the process of insertion of the drug, the action is relatively rough and irritating, causing uterine contractions, so there will be pain in the small stomach. It is recommended that the vulva must be washed first when the drug is used, and then the drug is inserted along the side wall of the vagina, finally reaching the posterior vaginal vault, and then slowly withdrawing the hand, which is the correct method of inserting the drug. If after correctly inserting the medicine, there is still pain in the small stomach, it is recommended to go to the hospital to do the appropriate examination to exclude the possibility of pelvic inflammatory disease. If vaginal nifurtimox is used, it is best to use the drug under the guidance of a doctor, and it is under the corresponding clinical indications that the drug can be used for treatment, and during the use of the drug can not have sex.