Vomiting with blood on the second day after drinking alcohol is considered to be caused by pathological factors such as cardia mucous membrane tear, peptic ulcer, rupture of gastric fundus vein and so on. 1. Tear of cardia mucosa: after excessive drinking, alcohol can stimulate the gastric mucosa and cause gastric spasm, resulting in vomiting. When the vomiting is severe, it can cause the mucous membrane of cardia and esophagus to be torn, which can lead to blood in vomiting the next day, mostly accompanied by pain in the upper part of the stomach body. 2. Peptic ulcer: If there are gastric ulcer and duodenal ulcer in the past, the ethanol in alcohol will corrode the ulcer surface and cause severe pain in the stomach, and after the ulcer surface is enlarged and deepened, it can invade the blood vessels of the stomach wall, and the blood vessels will rupture and bleed into the stomach, and the symptom of blood may appear in the next day’s vomiting. 3. Fundus venosus rupture: If you have cirrhosis of the liver, drinking alcohol can cause aggravation of the condition, and even induce varicose veins of the fundus venosus, rupture and bleeding, the next day when vomiting can appear symptoms of vomiting blood. Of course, the causes of vomiting blood the next day after drinking are not limited to the above diseases, so it is recommended to go to the hospital in time to find out the cause of vomiting blood after drinking and actively treat it to avoid delaying the condition.