Central memory CD4+ T cells belong to a type of T lymphocytes, which are an important part of the human immune system. Central memory CD4+ T cells play an important role in the immune system and can secrete cytokines to activate CD8+ T cells, which in turn effectively kill cells infected by pathogenic bacteria. Secondly, they can also inhibit the activation of target cells and assist in the elimination of tumor cells. In addition, the central memory CD4+ T cells will be attacked by the HIV virus, and therefore can usually reflect the severity of the disease. Generally speaking, the number of adult central memory CD4+ T cells per cubic millimeter is about 500 to 1600, and when the number is less than 500, timely measures should be taken for treatment. The number of central memory CD4+ T cells is an important indicator of the body’s immunity and can reflect the severity of many diseases. Seek timely medical attention when you are unwell to avoid progression of the disease.