Introduction of intestinal flora: It has a very important role in the human body and is considered as the “hidden organ” of the body, carrying the “second gene” of the human body, also described as a “super organism”. The intestinal flora regulates the intestinal homeostasis through the interaction with the host. The imbalance of intestinal homeostasis caused by various reasons will affect human health and lead to various diseases. The role of intestinal flora: 1, intestinal microorganisms can degrade the carbohydrates in food into monosaccharides for absorption. 2, intestinal flora can change the intestinal permeability, aggravate the bacterial infection. 3.The change of intestinal flora can not only cause obesity and diabetes, but also lead to cardiovascular disease. 4, intestinal flora can also play a role in non-alcoholic fatty liver disease by affecting the metabolism of bile acids. Intestinal flora and obesity: scientists after the experiment on mice proved that enterobacteria B29 and obesity are closely related. A large number of human experiments have confirmed that the intestinal bacteria Enterobacter cloacae B29 is one of the direct culprits of obesity,
This is also the first internationally recognized “obesity bacteria”. Intestinal flora and type 1 or 2 diabetes: In animal studies, the removal of intestinal bacteria from mice has been shown to cause type 1 diabetes more rapidly and severely. Feeding Lactobacillus yohimbe isolates to dairy mice susceptible to type 1 diabetes,
It suppressed their risk of developing type 1 diabetes. Direct intervention with gram-negative mucosal degrading bacteria in type 2 diabetic mice produced significant anti-inflammatory and hypoglycemic effects,
It is currently one of the promising strains for future application in the treatment of type 2 diabetes. Intestinal flora and NAFLD: Inflammation is associated with the pathogenesis of chronic liver disease and plays an important role in hepatocellular injury and fibrosis. Imbalance of the intestinal flora increases intestinal permeability,
Exposure of the liver to bacteria contributes to non-methylation, and these products stimulate endogenous immune system receptors that initiate relevant signaling pathways contributing to liver inflammation and fibrosis.