Long-term injection of hard lumps is due to the formation of chronic granuloma in the affected area. It is recommended to apply local hot compresses, external medication or lump removal surgery. 1. Local hot compresses: When hard lumps appear in long-term injections, it is recommended that local hot compresses be applied first to promote local blood circulation and reduce local swelling, so as to determine whether the hard lumps can subside. 2. Topical medication: You can use compound mucopolysaccharide ointment, diclofenac sodium ointment, safflower oil, Yunnan Baiyao aerosol and other medications. It can reduce the pain in the affected area, speed up the blood circulation and promote the hard lump to subside. 3. Hard lump excision surgery: if the hard lump exists for a long time and the above treatment effect is not obvious, the hard lump can be excised and sutured. It is recommended to consult the general surgery department of regular hospitals for diagnosis and treatment of hard lumps that appear after long-term injections.