Nipple peeling and itching may be related to local irritation, breast eczema, etc. Nipple peeling and itching caused by local irritation can be improved by topical moisturizing creams, etc. and removing the irritating factors. Breast eczema can be treated by general treatment, medication (tacrolimus ointment) and so on. 1. Local irritation: rough texture of clothes, underwear is too tight and other factors lead to nipple irritation, flaking, itching and other symptoms, you can wear loose, comfortable clothes to reduce the stimulation, topical moisturizing cream to improve the local dry irritation symptoms. 2. Breast eczema: to timely detach from the allergen, reduce external stimulation; external tacrolimus, pimecrolimus ointment and other calcium-modulated phosphatase inhibitors. When the itching is significant, you can take oral loratadine, cetirizine and other anti-inflammatory anti-itch. There are many factors that lead to nipple peeling and itching, it is recommended to consult a doctor in a timely manner to identify the cause of the relevant treatment, the specific use of drugs need to comply with the doctor’s instructions.