Right basal ganglia softening foci with gliosis means brain parenchymal necrosis. Brain softening foci are necrosis, liquefaction and resorption of brain tissues due to various causes, which result in the formation of localized cystic cavities of varying degrees of severity, filled with cerebrospinal fluid, and manifested as localized areas of hypodensity on CT. The causes of cerebral softening foci include traumatic brain injury, cerebral infarction, cerebral hemorrhage, and ischemic-hypoxic encephalopathy. A common cause of softened foci in the right basal ganglia region is cerebrovascular disease, and gliosis is inflammation and scarring of cells surrounding neurons in the brain. Softened foci with gliosis are generally suggestive of posterior phase lesions. If the examination has the above description, it is recommended to go to the hospital in time to clarify the etiology and intervene as early as possible to prevent recurrence.