In clinical practice, the amount of potassium chloride supplementation depends mainly on the degree of reduction in the patient’s blood potassium concentration. If the daily potassium supplementation varies from 40-80 mmol, and if each gram of potassium chloride is equivalent to 13.4 mmol of potassium chloride, about 3-6 grams of potassium supplementation is required daily. At present, potassium chloride is mainly used in clinical practice to correct hypokalemia and, like all other drugs, there are certain contraindications. Also, the rapid use of potassium chloride can cause a strong stimulation of the blood vessels, which can lead to vasculitis. In addition, potassium chloride can rapidly raise the blood potassium level, and if the blood potassium is too high or too low, it can have an adverse effect on the heart, so it is best to use potassium chloride under cardiac monitoring.