During pregnancy and menstruation is a special period, due to endocrine changes, blood glucose is prone to instability, so it is necessary to adjust the amount and method of insulin in time according to the characteristics of these two periods, mastering these methods, in order to control blood glucose up to standard. Generally in early pregnancy, due to gestational vomiting and eating less, the insulin demand of pregnant women is low; in the middle and late pregnancy, the placenta secretes a large number of hormones with insulin antagonism, resulting in an increase in the demand for insulin; after the delivery, due to the decrease in the level of insulin antagonism hormone, insulin needs to be reduced or even discontinued, or else the mother will experience hypoglycemia. In women with diabetes, blood glucose rises during menstruation; after menstruation, blood glucose returns to its original level. This is closely related to the changes in hormone levels in the female body. It is mainly due to the large release of estrogen and progesterone during menstruation, which aggravates insulin resistance. Therefore, it is necessary to strengthen blood glucose monitoring during menstruation and adjust insulin dosage in time according to the degree of blood glucose changes. Regardless of whether it is menstruation or pregnancy, it is necessary to frequently monitor blood glucose, and then adjust the amount of insulin according to the changes in blood glucose. Increase and decrease cannot be generalized.