Patients wake up at 1-2 o’clock at night can not sleep belongs to the sleep disorder, the formation of the reasons are mainly considered the following aspects: First, with the bad lifestyle has a relationship, if it is engaged in the night shift and other work, usually often in 1-2 o’clock shift or midnight habit of playing cell phones, games lead to biological clock disruption, will cause the biological clock disruption and lead to 1-2 o’clock at night always wake up can not sleep. Second, waking up at 1-2 o’clock at night may also be related to excessive psychological pressure, if the emotional anxiety, tension, neurasthenia may lead to the existence of such problems. Third, there may be other reasons for waking up at 1-2 o’clock, such as frequent nighttime urination, which makes it difficult for patients to fall back to sleep after waking up.