There are a variety of causes of high DNA fragmentation in men, and treatment can only reduce the rate of fragmentation, not completely cure DNA fragmentation. High sperm DNA fragmentation is relatively difficult to treat, and treatment can only reduce the rate of fragmentation, but generally does not provide a complete cure. Sperm DNA fragmentation is a condition that occurs when the sperm is affected during its formation, resulting in damage to the integrity of the sperm DNA, which can lead to DNA fragmentation. When a man has a high DNA fragmentation rate, he usually needs to undergo a detailed examination to find out the cause of the disease before treatment can be carried out. Common causes of the disease include poor living habits, genetic factors, inflammation of the reproductive tract, abnormal levels of sex hormones and other reasons, which usually need to be treated according to the cause of the disease. It is recommended that patients first go to the local hospital, after examination and then symptomatic treatment, do not unauthorized diagnosis and treatment.