HPV vaccine can mainly prevent cervical cancer, condyloma acuminatum and other diseases, but also includes some vaginal, vulvar and anal cancers. 1. Cervical cancer: most cervical cancers are related to HPV (human papillomavirus) infection, of which type 16 and 18 viruses are the high-risk factors for HPV virus infection. HPV vaccine can effectively block the continuous infection of some high-risk types of HPV viruses, so as to reduce the rate of cancerous changes in the cervical cancer and play a preventive role. 2. Condyloma acuminatum: The HPV vaccine can effectively prevent condyloma acuminatum and other diseases caused by type 6 and type 11 HPV virus infection. In addition, the occurrence of vaginal cancer, vulvar cancer and anal cancer is also related to HPV infection, all the HPV vaccination can also effectively prevent the occurrence of these diseases. The HPV vaccines currently on the market include nine-valent, four-valent, bivalent, etc. The range of diseases prevented by different vaccines is also different, and the age and interval requirements for vaccination are also different, so it is necessary to standardize the vaccination according to the individual’s situation under the guidance of the doctor. There are more than one hundred known HPV viruses, and HPV vaccination can effectively prevent some of these viruses and reduce the incidence of cervical cancer and condyloma acuminatum, but it is still necessary to do regular screening for cervical cancer.