The differences between type 2 diabetes and type 1 diabetes are as follows: 1. Type 1 diabetes: due to the obvious lack of insulin, it will cause obvious symptoms of three more and one less, i.e., polyuria, polydipsia, polyphagia and lethargy; 2. Type 2 diabetes: in the early stage of the disease, the lack of insulin secretion is not obvious, with the lack of insulin action, insulin resistance and insufficient insulin sensitivity, and insulin secretion deficiency can gradually appear in the middle and late stages. Overall, the pathogenesis of the two, as well as the clinical treatment modalities are significantly different, and the specific treatment should be based on the clinician’s diagnosis.