Strongly positive PPD is less likely to heal itself. Strongly positive PPD test result indicates that there may be active tuberculosis lesions in the patient’s body, and relevant examinations need to be conducted. X-ray is a common means of diagnosing tuberculosis, which can detect early tuberculosis lesions, and endoscopy is an important means of diagnosing tuberculosis, and if there are active tuberculosis foci in the patient, in general, it is impossible to cure by itself, and it is necessary to receive treatment in a timely manner. PPD is also known as tuberculin test, which is commonly used to detect Mycobacterium tuberculosis infection, but this type of test is unable to distinguish whether the positive test belongs to Mycobacterium tuberculosis infection or the immune response caused by BCG vaccination, so further examination is needed. PPD test results alone cannot accurately determine the condition of the disease, but must be combined with the characteristics of the medical history, clinical symptoms and other test results to make a comprehensive judgment. It is recommended that patients with such conditions seek prompt medical attention for a definitive diagnosis.