I am HPV, the Chinese name is human papillomavirus, is a recent wrist-level characters, although not yet into the “HPV door”, but has been “global storm”. I also want to say “two words”: 1, first of all, I have many family members, there are more than 100, but in fact to the cervical cause trouble is mostly HPV16 and HPV18 two only. 2, I am very proud because I achieved a German old man named Hausen, he actually found a clear causal relationship between me (HPV) and cervical cancer, and thus won the 2008 Nobel Prize in medicine. 3, I am a bit inferior, because I am actually a “mountain thief”, compared with other big players (hepatitis B virus HBV and hepatitis C virus HCV, both cause liver cancer; human immunodeficiency virus HIV, causing AIDS), I only in the cervical trouble, and as long as you are a little vigilant (once every two years cervical cancer screening ), I will hardly be a big deal. 4. As for how I got to you, sometimes God knows, you know and I know, but many times I really don’t know. Usually through sexual intercourse, but after contact with unclean sanitary ware and supplies may also be infected with me. 5. In fact, it is not true that once you get me, you will get cervical cancer! Only long term, continuous and high intimate contact with me can cause precancerous lesions of the cervix and cervical cancer. 6. It is said that 40% of women have contact with me at some time in their lives, but I usually appear as a visitor and mostly leave automatically. However, if you are in a bad state (declining immunity) and the environment is suitable (multiple sexual partners, unclean sex), I will get over it and settle down! 7.If the gynecologist finds out that I am haunting you, you will of course be nervous and unhappy, but, on the other hand, it is also a rather fortunate thing (by no means standing around talking!) . Because, after I was exposed, my family’s follow-up sabotage work mostly can not be done. 8. So, when should I be suspected and investigated? If a thin layer of cervical fluid-based cytology (i.e., TCT) suggests atypical squamous cells of undetermined significance (called ASCUS) or a higher degree of lesion, it’s time to get tested for HPV. If it is confirmed that I am not present (i.e., HPV negative), you can rest assured and repeat the TCT in six months; if it is confirmed that I am indeed present (i.e., HPV positive), you will need further testing with colposcopy and biopsy. If the TCT is found to be a higher level lesion, I should basically turn myself in and the test will just stay for the record. 9. As for how to investigate me, there are several ways: first, the cervical thin layer liquid-based cytology (TCT) report card will prompt, second, other methods, report HPV16, HPV18 positive; third, hybridization capture human papillomavirus test (HC2), in addition to reporting positive, but also report specific values (is semi-quantitative, and the amount of HPV has some correlation, but not absolutely parallel), is The most advanced screening method. 10. If a woman who is planning to get pregnant is infected with me, I recommend that you should get pregnant after you have sent the bulk of me away (the HPV value is significantly lower). The small number of people who have latched on will not usually affect the outcome of the pregnancy. 11. Even if I have caused you harm (e.g. various types of cervical precancer), you are still able to handle me. The bombardment attack (various physiotherapy and conization for cervical lesions) can wipe out most of my troops, that is, the so-called “cure is the cure”, and the remaining remnants are usually difficult to organize an effective attack. Moreover, your own immunity may eventually “invite me out”. 12. Basically, I can responsibly say that there are no oral drugs that can deal with me. Topical interferon in the cervix may have some effect. Western countries have developed new weapons, namely therapeutic HPV vaccines and preventive HPV vaccines (mainly for HPV16 and HPV18). According to their official releases, the results are still good. Anyway, I’m not horrible to the core, but you do need to pay attention, otherwise, there will really be some commotion! The author, Tan Xianjie, is a gynecologic oncologist at Peking Union Medical College Hospital, and is motivated by women’s excessive fear and misunderstanding of HPV. In recent years, the author has published many “academic papers” in authoritative journals that others do not read and do not see. Although it is impossible to publish these short articles in professional journals, I hope they will be of help to my friends. I’m sorry!