The absence of erythema on the skin may be lupus erythematosus. As lupus erythematosus is a chronic autoimmune disease, it is not an ordinary skin lesion, nor is it just a simple skin and mucous membrane damage. Some hidden patients may not have skin lesions such as erythema and rash throughout the course of the disease, but with the development of the disease, it may damage various organs in the body, so the absence of erythema in the skin may be lupus erythematosus. When lupus erythematosus is caused by abnormalities in the immune function of the patient, it may lead to the production of a large number of antibodies in the patient’s body, and the immune complexes formed by the antibodies may be deposited in various tissues and organs, leading to lesions in various tissues and organs of the body of the patient, such as damage to the kidneys, damage to the vascular system, and damage to the central nervous system, and so on. Patients suspected of having lupus erythematosus are recommended to go to the hospital in time for relevant examinations to make a clear diagnosis, and under the guidance of the doctor to carry out regular treatment.