The Department of Chemotherapy and Biotherapy of Oncology of our hospital is a professional department composed of multidisciplinary teams to serve elderly oncology patients. In the clinical diagnosis and treatment, we have introduced the most advanced Comprehensive Geriatric Functional Assessment (CGA) in international geriatric oncology, in order to clearly assess the functional status and co-morbidities of the elderly patients, to guide the evaluation of the risk of oncology treatment, and to formulate an individualized treatment plan, in order to achieve the therapeutic goals of improving the quality of life and prolonging the survival of the elderly patients. The goal is to improve the quality of life and prolong the survival effectively. The Comprehensive Geriatric Assessment (CGA) includes the Katz Index of Activities of Daily Living (ADL), the Lawton Instrumental Activities of Daily Living (IADL), the Eastern Cooperative Oncology Group Physical Status Score (ECOG PS), the Folstein Mini Mental State Examination, and the Yesavage Geriatric Depression Score. Malnutrition, overdose, and psychosocial status may be assessed by an oncologist versus a clinical pharmacist, respectively. Biological characterization of the patient’s age, gender, family history, past history, diagnosis, and tumor stage are also included.The average CGA evaluation takes about 2 hours, and each patient undergoes a multidisciplinary discussion to develop a further individualized treatment plan. Jing Liang, Department of Chemotherapy, Shandong Qianfoshan Hospital Comprehensive Geriatric Functional Assessment (CGA) is an effective tool for evaluating tumor risk and developing treatment plans for elderly oncology patients, focusing on screening for potential or existing health problems in elderly patients. There are a large number of elderly patients with functional limitations, dementia and depression, overuse of medications, and malnutrition that need to be detected by CGA assessment.The ADL living status assessment found that 20% of the patients were functionally dependent or in need of help, and the IADL living status assessment showed that 55% of the patients were in need of help.The Yesavage Geriatric Depression Assessment found that 23% of the elderly patients were depressed and 15% had dementia. An assessment of nutritional status revealed that 30% of patients had mild or significant malnutrition. In addition, there was substantial overmedication in the elderly population, with 57% of patients taking three or more medications, 35% taking five or more medications, and 7% even taking ten or more medications.The ECOG PS General Status Score found that 20% of the patients scored a poor general status of 2.0 or higher, with an average comorbid condition of 3.5, with hypertension, coronary artery disease, and diabetes being the major common comorbidities. According to the National Cancer Research Network (NCCN) Clinical Guidelines for Oncology in the Elderly, the results of the above functional status assessment will play a decisive role in the assessment of the patient’s tumor risk and the development of an oncology treatment plan.