Abnormalities in renal metabolism leading to potassium deficiency can be treated, mainly by means of treating the primary disease and potassium supplementation. 1. Treatment of primary disease: conduct a series of examination to identify the primary disease of the patient, and carry out targeted treatment for the primary disease, for example, the primary disease includes renal artery stenosis, nephrolithiasis, potassium deficiency nephropathy and so on. 2. Potassium supplementation: Serum potassium is 3.0~3.5 mmol/L in mild potassium deficiency, 2.5~3.0 mmol/L in moderate potassium deficiency and 2.0~2.5 mmol/L in severe potassium supplementation. Potassium-rich foods can be consumed, such as meat, green vegetables, fruits, beans to improve, the way of potassium supplementation includes intravenous and oral medication for potassium supplementation, the medication for potassium supplementation includes potassium chloride, potassium citrate, potassium acetate, potassium glutamate and so on, and the severe low potassium needs intravenous drip for potassium supplementation. Severe low potassium needs intravenous potassium supplementation. The above medications should be used according to the doctor’s prescription, and should not be used on one’s own. For patients with potassium deficiency caused by renal metabolism abnormality, it is recommended to go to the hospital in time for consultation and standardized treatment under the guidance of doctors.