Osteoarthrosis (OA) is the most common disease and major cause of disability in middle-aged and elderly people, seriously affecting patients’ quality of life and social productivity. With the process of population aging, numerous countries have entered the aging society. The current number of people over 60 years old in China is over 130 million, and it is expected that the total number of people over 60 years old will exceed 200 million by 2015. According to WHO estimates, 10% of the world’s population over the age of 60 suffers from OA. 80% of OA patients have mobility problems, and 25% are unable to perform daily activities. The prevalence of OA in the 20-year-old age group is reported to be only 20%, while the 70-year-old age group is 85%. Statistics show that about 40 million adults in the United States suffer from arthritis, of which OA accounts for 43%, 90 percent of women and 80 percent of men over 65 years of age suffer from this disease. With the increasing aging of the world’s population, the incidence of OA is on the rise globally, and degenerative joint diseases have become one of the most important topics of medical research today. Strengthening research on age-related osteoarthritis is conducive to improving the quality of life of the elderly, promoting social and economic development, and improving the health of the nation.