Stones can cause nausea and vomiting when they are painful, and this condition is most often seen in upper ureteral stones. Because of the distribution of nerves in the upper ureter, some of them enter the abdominal ganglion, so there is a common traffic branch with the presence of the gastrointestinal tract. When a stone in the upper ureter irritates the local area, it can produce gastrointestinal spasms, and nausea and vomiting. In some patients, the first symptom is nausea and vomiting, and only later the symptoms of back and abdominal pain appear. If extracorporeal shock wave lithotripsy and pain management are given, the nausea and vomiting can be relieved or disappear immediately after the stone is gradually discharged into the lower part of the ureter or the bladder is emptied. It is recommended that for patients with painful stones, extracorporeal shock wave lithotripsy, symptomatic pain relief or surgery should be given after the size and location of the stones have been clarified in the hospital. In addition, some patients with nausea and vomiting are not caused by gastrointestinal diseases and need ultrasound examination of the urinary system to rule out the presence of stones.