Mitral valve prolapse with insufficiency of closure is a more serious condition. Basically, mitral valve prolapse is usually accompanied by valvular insufficiency. The severity of the valvular insufficiency determines the degree of regurgitation, which can cause significant damage to the heart. For example, mitral valve prolapse can lead to heart failure and pulmonary stasis, which can cause the patient to wake up at night or not be able to lie down at night, called paroxysmal dyspnea. Therefore, patients with severe mitral valve prolapse need to be treated for this condition, which is usually divided into two main types of treatment: medication and surgery. Mild mitral valve prolapse resulting in insufficiency requires medication to reduce the load on the heart. If medication is ineffective, further surgical intervention is required. There are two types of surgical interventions. Patients with good valve function and good leaflet structure can undergo mitral valvuloplasty. If the quality of the valve is poor and there is no way to perform valvuloplasty, only valve replacement can be performed. There are two types of valve replacement: mechanical and biological. Therefore, mitral valve prolapse with incomplete closure depends on the condition of the patient, and surgery is required for severe cases.