Cirrhosis total bilirubin, direct bilirubin, indirect bilirubin are high, you can take medicine for the cause of the disease and take some liver protection drugs, such as reduced glutathione tablets, compound glycyrrhizin capsule, bisabolol tablets and so on. 1. Taking medicine for the cause: if the cirrhosis is caused by hepatitis due to viral infection, you should take antiviral drugs to lower bilirubin, such as lamivudine tablets, sofosbuvir tablets, dalatasvir hydrochloride tablets, etc.; if it is a biliary problem such as biliary tract stones that lead to high bilirubin, you can take cholagogic medicine, such as anti-inflammatory cholagogic tablets, arbutin bile deoxycholic acid capsule, etc., which can play the role of lowering bilirubin. 2. Hepatoprotective treatment: high bilirubin can be routinely carried out hepatoprotective treatment, such as reduced glutathione tablets, compound glycyrrhizin capsule, bisabolol tablets and so on, can protect the function of the liver. In conclusion, high bilirubin in cirrhosis should be treated with medication for the cause of the disease and liver protection drugs. The above treatments should be carried out under doctor’s guidance.