When significant bleeding is found in the fundus, the first step is to look for the cause of the bleeding in the eye. The more common clinical causes of hemorrhage may be central retinal vein obstruction, diabetic retinopathy, hypertensive retinopathy, highly myopic eye complications, age-related macular degeneration, and fundus hemorrhage after ocular trauma. Therefore, after the diagnosis is clear, treatment should be directed at the cause. In the early stage of hemorrhage, it is usually considered to treat with hemostatic drugs first. After three days of hemorrhage, it is usually considered to use various drugs to activate blood circulation and remove blood stasis, such as salvia drugs, or Chinese herbal medicine. In addition, further examination by fundus angiography is recommended to determine whether there is a significant non-perfusion area in the fundus, especially if there is central retinal vein obstruction or diabetic retinopathy, which requires prompt fundus laser treatment. If macular edema is also present, vitreous humor injection and anti-VEGF treatment are required. If the fundus hemorrhage is accompanied by significant blood accumulation in the vitreous cavity or a possible retinal detachment, it is best to consider prompt surgical treatment. Because a large amount of blood in the vitreous cavity cannot be absorbed on its own, it may lead to serious complications if left untreated.