Some non-dietary causes of obesity

There are a lot of people in life will appear obesity phenomenon, after the emergence of this situation on the patient’s body is very harmful, and there is an impact on the life, affecting the image, so we should pay attention to the common causes of this disease, then, what are the factors of obesity? What are the causes of obesity? 1, genetic factors Epidemiological investigations have shown that: some of the simple obese people have a tendency to family morbidity. Both parents are obese, their children suffered from simple obesity than both parents of normal weight children born 5 to 8 times higher.Vanllallie on 1333 children born during the period of 1965 to 1970 conducted a longitudinal investigation also found that one parent has obesity, the children born with the age of their children, they are more than the normal ratio (oddratio) also increased, 1 to 2 years of age, the children are more than the normal ratio (oddratio) also increased. With the increase, 1 ~ 2 years old obese children to adult early obesity for 1.3, 3 ~ 5 years old obese for 4.7, 6 ~ 9 years old obese for 8.8, 10 ~ 14 years old 22.3, 15 ~ 17 years old 17.5. 2, neuropsychiatric factors It is known that human beings and a variety of animal hypothalamus there are two pairs of neural nuclei related to ingestive behavior. One pair is the ventral contralateral nucleus (VMH), also known as the satiety center; the other pair is the ventral lateral nucleus (LHA), also known as the hunger center. When the satiety center is excited, there is a feeling of satiety and refusal to eat, and when it is destroyed, there is a great increase in appetite; when the hunger center is excited, there is a strong appetite, and when it is destroyed, there is anorexia and refusal to eat. Both of them regulate each other and restrain each other, and are in a dynamic equilibrium under physiological conditions, so that the appetite can be regulated in the normal range and the normal body weight can be maintained. When the hypothalamus lesions, regardless of the sequelae of inflammation (such as meningitis, encephalitis), trauma, tumors and other pathological changes, such as the destruction of the medial nucleus of the abdomen, the lateral nucleus of the abdominal function of the relative hyperphagia and anorexia, causing obesity. Conversely, when the ventral lateral nucleus is destroyed, the ventral medial nucleus is relatively hyperfunctional and anorexic, causing wasting. In addition, this area has close anatomical connections with higher nervous tissue, which can also regulate the feeding center to a certain extent. The blood-brain barrier is relatively weak at the hypothalamus, an anatomical feature that allows a variety of biologically active factors in the blood to migrate there and thus have an effect on feeding behavior. These factors include: glucose, free fatty acids, norepinephrine, dopamine, 5-hydroxytryptamine, insulin, etc. In addition, psychiatric factors often affect appetite, the function of the food bait center is subject to the mental state, when mental overstress and sympathetic excitation or adrenergic nerve stimulation (especially the α-receptor predominance), appetite suppression; when the vagus nerve excitation and insulin secretion increases, appetite is often hyperactive. The medial nucleus of the abdomen is the sympathetic nerve center, and the lateral nucleus of the abdomen is the parasympathetic nerve center, both of which play an important role in the pathogenesis of this disease. 3.Hyperinsulinemia In recent years, the role of hyperinsulinemia in the development of obesity has been striking. Obesity often coexists with hyperinsulinemia, but it is generally believed that hyperinsulinemia causes obesity. The release of insulin in hyperinsulinemic obese individuals is approximately three times that of normal individuals. Insulin has a significant role in promoting fat accumulation, and it has been suggested that insulin can be used as an indicator of total body fat and, in some sense, as a monitoring factor for obesity. Some people think that plasma insulin concentration and the overall amount of lipid was significantly positively correlated. 4, brown adipose tissue abnormal brown adipose tissue is a kind of adipose tissue found in recent years, and mainly distributed in the subcutaneous and visceral white adipose tissue around the opposite. Brown adipose tissue has a limited distribution range, only in the interscapular area, the back of the neck, the axillary area, the mediastinum and around the kidneys, and its tissue appearance is light brown, with relatively small changes in cell volume. White adipose tissue is a form of energy storage, the body will be excess energy in the form of neutral fat storage in between, the body needs energy, neutral fat hydrolysis in the adipocytes to use. The volume of white adipocytes varies greatly with energy release and energy storage. Brown adipose tissue is functionally a thermogenic organ, i.e., when the body ingests or cold stimulus, brown adipocyte fat burning, thus determining the body’s energy metabolism level. These two conditions are referred to as ingestion-induced thermogenesis and cold-induced thermogenesis, respectively. A healthy diet can help prevent this disease. We need to pay attention to the changes in the body, the usual life should pay attention to the conditioning matters, scientific nutritional health care, and eat less greasy things, we should not ignore the development of the disease, choose professional treatment, which is more conducive to the recovery of the disease, so as not to bring more impact. Obesity is not a disease, but the root cause of many diseases. Control your weight, you can get rid of many diseases.