Hard to get up shall refer to the male erectile dysfunction disease, the common treatment drugs for people diagnosed with this disease are mostly oral or injectable forms, such as type 5 phosphodiesterase inhibitors, vasoactive drugs, etc., and topical drugs are less frequently used. 1. Oral therapy drugs: is currently the simplest and most acceptable first-line treatment for erectile dysfunction. (1) Type 5 phosphodiesterase inhibitors: such as sildenafil citrate tablets, tadalafil tablets, etc., are currently the preferred treatment drugs for erectile dysfunction. Such drugs are prohibited for those who are allergic to them or are using nitrate drugs, and adverse reactions such as headache and visual abnormalities may occur during the use of the drugs. (2) Androgenic preparations: such as testosterone undecanoate soft capsule, etc., suitable for low androgen levels to cause disease. These drugs are prohibited for those with confirmed or suspected prostate cancer. Adverse reactions include acne, gastrointestinal discomfort, etc. 2. Injectable therapeutic drugs: applicable to those who are ineffective in oral drug treatment. Mainly use vasoactive drugs, such as opioid, prostaglandin, phentolamine, etc. These drugs are prohibited for those who are allergic to them or have serious cardiac insufficiency, renal insufficiency, etc. Adverse effects include tachycardia, vomiting, etc. 3. Topical therapeutic drugs: such as testosterone patches, prostaglandin E1 cream, etc., less used. It is prohibited for those who are allergic to it, and the adverse reactions are mostly localized redness, swelling, rash and so on. In summary, although the existence of topical drugs for erectile dysfunction, but clinically less used. Therefore, the diagnosis of this disease must be under the guidance of the doctor according to the actual situation of the choice of medication, do not dispose of their own, blind use of drugs, so as not to cause adverse consequences.