Esophageal hyperplasia may be caused by reflux esophagitis, esophageal cancer and other diseases, which need to be treated with medication, surgery, endoscopy, radiotherapy and chemotherapy according to the cause. 1. Reflux esophagitis: common symptoms include abdominal pain, heartburn, acid reflux and belching. Patients need to use proton pump inhibitors such as omeprazole and rabeprazole, or H2 receptor blockers such as ranitidine and cimetidine as prescribed by the doctor. At the same time, the application of gastric stimulants, such as cisapride, itopride, etc., and colloidal bismuth, aluminum thioglycollate and other gastric mucous membrane protective agents are also required. For patients with ineffective drug treatment, endoscopic radiofrequency ablation, gastric fundoplication, magnetic sphincter augmentation and other surgical treatments should be adopted. 2. Esophageal cancer: main symptoms include choking sensation, difficulty in eating and abdominal pain. Clinical treatments for this disease include minimally invasive thoracolaparoscopic esophagectomy, conventional open thoracic surgery, etc., as well as endoscopic treatments such as endoscopic mucosal resection, radiofrequency ablation, photodynamic therapy, endoscopic submucosal dissection, etc. Some patients may also need to cooperate with doctors for the treatment of esophageal cancer. Some patients may also need to cooperate with doctors for radiotherapy or apply chemotherapy drugs such as paclitaxel and cisplatin. When patients are examined for the presence of esophageal hyperplasia, they need to undergo further relevant examinations to clarify the specific cause and cooperate with doctors to actively treat the primary disease.