Urine test ketone bodies and glucose may be present at the same time, normal people urine routine examination of urine ketone bodies and urine glucose are negative, diabetic patients when the blood glucose elevation is obvious, a large amount of glucose with the urinary excretion, more than the reabsorption capacity of the renal tubules, glucose in the urine, with the degree of elevation of glucose is different, the urine glucose can be manifested as (+) to (++++). Urinary ketone bodies, on the other hand, is the body’s utilization of carbohydrate dysfunction or lack of carbohydrates, only lipolysis to supply energy, lipolysis will lead to excessive production of ketone bodies, ketone bodies is a very acidic substance, ketone body production is excessive will lead to blood ketone body elevation, urine ketone body positive, normal people can appear in the state of starvation urinary ketone bodies. Depending on the degree of elevation of ketone bodies, urinary ketone bodies can show (+) to (++++), severe ketone body elevation may also lead to ketoacidosis. Therefore, when a patient has both ketone bodies and glucose on a urinalysis, the patient should be considered to have diabetic ketosis, or a state of diabetic ketoacidosis. Both diabetic ketosis and ketoacidosis are acute complications of diabetes mellitus that require aggressive management.