Scabies nodules on the scrotal skin are very difficult to fade away naturally, and usually require a trip to the hospital to receive standardized diagnosis and treatment before they can fade away. Scabies nodules on the scrotum skin of patients who do not do the targeted treatment for a long time, there may be a variable number of reddish hard nodules, accompanied by a strong itching sensation, will seriously affect the patient’s sleep and quality of life. Scabies nodules have a layer of hard tissue on the outside, the action of drugs can effectively promote the recovery of scabies nodules, early treatment can be applied with sulfur ointment. If necessary, hormonal drugs such as trimethoprim and betamethasone can be injected into the skin lesions. It is recommended that patients go to the hospital in time, do not delay the condition. Drugs need to be used in accordance with medical advice.