If diabetic patients have symptoms such as vomiting, nausea and poor appetite during treatment, the following causes should be analyzed: 1. It is common in diabetic ketoacidosis, which will manifest as symptoms of the digestive tract, such as nausea, vomiting and symptoms of loss of appetite. If there is diabetic ketosis or diabetic ketoacidosis, insulin should be given in time to control blood glucose, and active rehydration to eliminate ketosis. 2, some patients in oral metformin will also appear gastrointestinal symptoms, such as nausea, vomiting and other symptoms, the symptoms can be relieved after discontinuing metformin. 3.Patients with a long history of diabetes have symptoms of gastroparesis, some patients will have abdominal distension, nausea, vomiting and loss of appetite, but it is necessary to actively exclude whether there are gastrointestinal diseases, and if necessary, improve the gastroscopic examination to further determine the diagnosis of diabetic gastroparesis.