The application of dydrogesterone in the process of endometrial thickening has the effect of inducing atrophy of the endometrium. In the process of endometrial thickening, if the ultrasound indicates that the thickness of the endometrium is greater than normal, endometrial scraping should be performed at this time. If the pathology of the endometrium after the scraping suggests hyperplastic changes, or poor secretion, the use of dexprogesterone can be continued. In the case of atypical endometrial hyperplasia, it is not just a question of applying depo-progesterone, but of administering a high dose of progesterone to reverse the hyperplastic state of the endometrium.