The four drugs for tuberculosis are best taken in the morning on an empty stomach. Tuberculosis four drugs are isoniazid, rifampicin, pyrazinamide, ethambutol, four drugs should be taken in the morning on an empty stomach at one time, is conducive to the absorption of the drug, and the effect of sterilization is also better. In the process of taking, avoid taking with milk, tea, coffee, drinks, so as not to affect the effect of the drug, and increase the adverse drug reactions. Part of the population can not tolerate fasting medication, stomach upset, you can adjust the time of taking the drug to take before bedtime, or take 2 hours after meals. During the period of taking medication should be supplemented with high protein, high calorie, high vitamin food, avoid eating too much fat during the period of taking medication, prohibit drinking alcohol, keep taking medication regularly every day to avoid missing doses. Tuberculosis four kinds of drugs to the morning on an empty stomach to take a one-time effect is better.