Cold hands and feet of 40-year-old men are often considered to be spleen and stomach yang deficiency, liver and stomach deficiency, qi and blood deficiency, etc. They can be treated by taking Chinese patent medicines, herbal foot soaks or acupuncture. It is recommended to choose the appropriate method to administer the treatment under the guidance of a professional physician. Proprietary Chinese medicines such as Lizhong Pill, which has the effect of warming and tonifying the middle yang, can be used to treat fear of cold limbs caused by yang deficiency of the spleen and stomach; Wu Zhu Tang, which has the effect of warming the middle yang and tonifying the middle yang, lowering the rebelliousness and stopping vomiting (stopping the upward rush of gastric qi and stopping the vomiting) can be used to treat cold limbs caused by deficiency of the liver and stomach; and Ginseng Nourishing Rong Pill, which warms and tonifies qi and blood, can be used to treat cold limbs and feet caused by deficiency of qi and blood. Note: The body is strong and solid without deficiency should be avoided. Mugwort leaves, dry ginger boiled water foot soak belongs to the external treatment method, can dredge the meridians, pass qi and blood, help to improve the symptoms of cold hands and feet. Acupuncture therapy or massage stimulation of acupoints such as Yongquan, Kidney Yu, Foot Sanli, etc., can play a role in stimulating yang qi, dredge meridians and channels, and harmonize yin and yang, and therefore can alleviate the symptoms of cold hands and feet. It is recommended that patients with severe cold hands and feet seek medical attention in a timely manner, under the guidance of a doctor to avoid delaying the condition or adverse reactions.