First of all, the cause of blood in urine should be clearly defined, which commonly includes urinary tumor, stone, trauma, tuberculosis, etc. Pharmacological treatment and surgical treatment should be carried out according to the specific cause of the disease. 1. Urological tumor, almost all urological tumors such as kidney cancer, bladder cancer and prostate cancer can cause hematuria, which is initially microscopic hematuria, and then evolves into painless gross hematuria. The general treatment is mainly surgery, together with radiotherapy, chemotherapy and targeted therapy (sunitinib, erlotinib, etc.). Specific treatment means should be combined with the actual situation. 2. Stones, urinary stones can also lead to hematuria, which is mainly manifested as pain in the waist or abdomen, and the treatment is mainly surgical. 3. Trauma, such as urethral injury, kidney injury, bladder rupture, etc., will appear naked eye hematuria, the main treatment for surgical repair of ruptured organs. 4. Tuberculosis, urinary tract tuberculosis patients, there will be frequent urination, urinary urgency, urinary pain and other bladder irritation signs with terminal hematuria. Treatment is mainly anti-tuberculosis treatment (isoniazid, streptomycin, etc.). Appearance of blood in the urine, need to consult a doctor in time, follow the doctor’s instructions for reasonable treatment, drugs need to be rationally applied under the guidance of the doctor.