Elevated alanine aminotransferase during pregnancy requires antiviral, hepatoprotective and enzyme-lowering treatments to identify the cause, as well as rest and regular rechecks of liver function. The causes of AAT during pregnancy are commonly attributed to viral hepatitis, fatty liver, overwork and other causes, which need to be treated according to the causes. For the non-viral hepatitis caused by maternal ghrelin, such as fatty liver, overwork and other causes, can be applied to drugs to protect the liver and reduce enzyme treatment, such as oral compound glycyrrhizin tablets, etc., the specific drug program should be carried out under the guidance of the doctor. If the condition is serious, infusion therapy is needed. At the same time, excessive diet should be corrected, pay attention to rest, reduce the burden on the liver. In case of elevated ghrelin during pregnancy due to viral hepatitis, antiviral combination therapy such as tenofovir can be added on the basis of the above treatment, which should be applied under doctor’s guidance. In addition, the fetus needs to be vaccinated after birth to block mother-to-child transmission of the virus.