When anal polyps develop malignant lesions, they may induce perianal cancer. Perianal cancer is a non-infectious disease, HPV infection is a high-risk predisposing factor, while the squamous epithelium around the anus is a lesion triggered by long-term stimulation of chronic inflammation such as suppurative sweating inflammation, warts, hemorrhoids and so on. Patients will have perianal discomfort or itching in the early stage, some patients have rectal bleeding symptoms, small lumps are touched in the anal verge, accompanied by pain, and there will be tenderness after the formation of ulcers, and after the tumor metastasis, it is common to see enlarged inguinal lymph nodes, and there will be systemic failure manifestations such as anemia and malignant stroma in the late stage. It is recommended that patients go to regular hospitals in time, under the doctor’s diagnosis, according to the patient’s specific condition, the implementation of targeted treatment; patients should actively cooperate with the treatment, the life of a reasonable diet, regular work and rest, and comply with the doctor’s instructions.