Multiple enlarged lymph nodes in the neck should be examined with color ultrasound of the neck as well as enhanced CT to further clarify the diagnosis, while commonly lymphoma, which also needs to be combined with CT examination of the chest and abdomen, is a common malignant tumor. The diagnosis of solid tumor should be confirmed by local lymph node biopsy. After the diagnosis is clear, systemic intravenous chemotherapy should be chosen to control the development of the tumor, and during the treatment period, attention should also be paid to monitoring the changes of laboratory indicators to prevent the emergence of related complications. At the same time, patients should be advised to increase the nutrition of diet and eat more high protein food. In addition, there are some patients who have lymph node metastasis in the neck due to malignant tumors in distant organs, and they also need to clarify the pathology and can control the rapid development of the tumor through radiation therapy, intravenous chemotherapy, targeted therapy, etc.