Xenadrine generic name Progesterone Vaginal Extended-Release Gel, especially itchy after use is usually not normal, it may be an allergy or an adverse reaction. Progesterone Vaginal Extended-Release Gel belongs to the progestogen class of drugs, suitable for supplemental treatment of progesterone in assisted reproductive technology. The drug is contraindicated in patients with known hypersensitivity to the product, with unexplained vaginal bleeding, acute porphyria, hepatic dysfunction or hepatic disease, known or suspected progesterone-sensitive malignancies, thromboembolic disease, thrombophlebitis or a history of hormone-related such disease, cerebral hemorrhage or a history of such disease, and induced abortion. Adverse reactions such as abdominal pain, perineal pain, headache, constipation, diarrhea, nausea, vomiting, joint pain, as well as itching, rash and acne may occur after use of the drug. Therefore, itching after using the drug may be due to the adverse reaction of the drug. It may also be a manifestation of allergy to the drug, which should be promptly discontinued, and if necessary, consult a doctor for treatment. Specific medication should be carried out under the guidance of a specialist, not unauthorized use of medication.