The generic name of isotretinoin is isotretinoin soft capsule, a few patients overdose may lead to mild elevation of bilirubin, the appearance of high bilirubin may also be hepatitis, gallstones and other causes.
1. Overdose: isotretinoin soft capsules are mainly metabolized in the liver, long-term use or excessive dosage, easy to cause liver function damage, a few patients may appear bilirubin and other mildly elevated, usually reduce the dosage or discontinue the drug can be restored to normal values.
2. Hepatitis: Infection of viruses and other liver cell damage, bilirubin conversion, transportation and other abnormalities, bilirubin may be elevated. It can be diagnosed by routine blood test and pathogen test.
3. Gallstones: stones blocking the bile ducts, bile excretion obstacles, may cause elevated bilirubin, but also may have pain in the liver area, nausea and other uncomfortable symptoms, you can do ultrasound and so on to further clarify the diagnosis.
The drug is often used in the treatment of nodular acne, etc. The use of the drug may cause dry skin, allergy, inflammatory bowel disease, thrombocytopenia and other adverse reactions. The drug is contraindicated in people who are allergic to the drug, pregnant as well as breastfeeding women, and should be used with caution in diabetes, women of childbearing age, and others. The drug should not be used together with tetracyclines.
The presence of high bilirubin during the administration of the drug may also be due to other reasons such as strenuous exercise, cirrhosis of the liver, jaundice, etc. The cause should be promptly identified under the supervision of a doctor and reasonable treatment should be carried out. If you need to use the drug, it should be used reasonably under the guidance of a doctor.