In life, after some accidental damages, brain diseases and other surgeries, there is a possibility of causing skull defects, and the top of the head will collapse or expand. Once the skull is defective, if it is not repaired for a long time, the patient may have dizziness, headache, pain at the edge of the defect, and other adverse reactions, and it may make the patient have fear, depression, and low self-esteem, so the skull defect must be repaired as soon as possible. Experts pointed out that the best time for cranial repair surgery is generally between 2-3 months after surgery, some patients can also decide to repair time according to their own condition, while the choice of repair material is also related to the overall shape of the postoperative recovery, good materials not only good postoperative recovery, but also as far as possible to avoid some postoperative complications. For cranial repair materials, most hospitals still use titanium mesh as the repair material, according to clinical patients’ postoperative response, titanium mesh is not only the presence of postoperative exposure, but also because it is a metal material, the patient is easy to be sensitive to hot and cold stimulation, easy to produce or store fluid in the subcutaneous tissues are easy to be infected, and the lesion localized discomfort or chronic pain may occur. Such as temporal fossa, eyebrow frame and other special parts of the repair after the appearance of poor results and so on. With the unremitting efforts and exploration of medical experts, a new high-tech materials can be very good to meet the basic requirements of patients for cranial bone repair, the material is polyether ether ketone PEEK material, PEEK material has a high temperature resistance, corrosion resistance, ray transmittable, can be complex shaping advantages, and can be well avoided after the operation of the titanium mesh and other materials exist in the complications, so that many patients in the postoperative period are better able to recover. The material is used in our clinic. We have used this material in our clinic, and it has been used to repair thousands of patients with skull defects, and the patients are satisfied with the results of the surgery.