Acute elevated blood glucose should promptly seek medical attention, under the guidance of the doctor to clarify the cause of the disease, and then for the cause of the treatment. Elevated blood glucose can occur in stress, diabetic ketoacidosis, hyperosmolar hyperglycemic syndrome and other diseases, such as diabetic ketoacidosis treatment mainly includes general treatment, active rehydration, insulin application, correction of electrolyte disorders, correction of acidosis. The medication should follow the doctor’s instructions. 1. General treatment: oxygen inhalation, suggesting intravenous access, testing blood pressure, blood glucose, oxygen saturation, etc., checking blood and urine routine, electrolytes, renal function, blood gas analysis, etc. 2. Active rehydration: fast then slow, timely potassium supplementation, helps to correct acidosis. Often choose isotonic sodium chloride, according to the peripheral circulation, blood pressure, urine output, mental and cardiovascular status to adjust the infusion volume and speed. Meanwhile, gastrointestinal rehydration is encouraged to reduce the amount of intravenous rehydration. 3. Insulin application: small dose or physiological dose of insulin was routinely given for control, and the blood glucose was reduced to 13.9 mmol/L, which was changed to 5% dextrose or glucose saline added to insulin for use. If blood glucose does not drop significantly after 2 hours of treatment, insulin should be doubled. 4. Correct electrolyte disorders: intravenous insulin needs intravenous potassium supplementation after urine, no urine or urine <30ml/h, suspend potassium supplementation, need to test blood potassium and renal function. If calcium and magnesium are reduced, supplement as appropriate. 5. Correct acidosis: in combination with severe acidosis, 5% sodium bicarbonate drip should be given, which should not be too fast or too much, so as not to induce or aggravate cerebral edema. Acute elevation of blood glucose, it is recommended to go to the hospital in time for treatment, usually must follow the doctor's instructions for medication.