You can’t drink alcohol before or after penicillin infusion for the following reasons: 1, it is possible that if you drink alcohol after penicillin infusion, the alcohol will interact with the penicillin inside the bloodstream, thus producing other substances. If these substances are harmful, they will have more or less adverse reactions to the body.2. If penicillin is affected by alcohol, it is very likely that the anti-infective effect of penicillin will be weakened.3. If penicillin has a delayed allergic reaction, that is, there are no allergic symptoms at the time of infusion, but there is a delayed allergic reaction a few hours or 1-2 days after the infusion. After drinking alcohol, it is possible that alcohol promotes blood circulation throughout the body, leading to a more severe allergic reaction, the most serious may lead to anaphylactic shock, which may be life-threatening.