Sore and itchy nose and runny nose after running are considered to be caused by vasomotor rhinitis or allergic rhinitis. Relief includes medication such as nasal glucocorticoids, antihistamines, nasal decongestants, and nasal anticholinergics. 1. Vasomotor rhinitis: it can be caused by mental tension and environmental temperature change, manifested as sneezing, runny nose, itchy nose, nasal congestion and other symptoms. Apply nasal glucocorticoid, such as fluticasone propionate, mometasone furoate nasal spray, etc.; nasal antihistamines, such as azelastine hydrochloride nasal spray; nasal anticholinergics, such as ipratropium bromide nasal spray, etc., to relieve the symptoms. 2. Allergic rhinitis: Inhalation of allergens during running can cause allergic rhinitis, resulting in itchy nose, sneezing, runny nose, nasal congestion and other symptoms. Apply second-generation antihistamines, such as cetirizine hydrochloride, loratadine, etc.; nasal glucocorticoids, such as fluticasone propionate, mometasone furoate nasal spray, etc.; nasal decongestant, such as furosemide nasal drops, etc., to relieve the symptoms. After running the nose sore itchy runny nose, it is recommended to go to the hospital, diagnosis is clear and follow the doctor’s prescription medication.