Chest X-ray nodular hyperdense shadow is a term used to describe the image of a lesion in the lungs, usually referring to the presence of an unusual lesion in the patient’s lungs. Clinically, nodular hyperdense images on chest radiographs are mostly caused by lung tumors, lung infections, and pulmonary nodular disease, and the hyperdensity suggests that the lesion may not be of low density. The likelihood of malignancy is generally low if the patient has a solid density nodule, and relatively high if the nodule is semi-solid. Therefore, the simple nodular hyperdense image on chest X-ray does not confirm the diagnosis of the disease, and a number of other related tests, such as routine blood tests, blood sedimentation, and C-reactive protein, are also required. If the white blood cells or neutrophils are high, the blood sedimentation is positive, and the C-reactive protein is positive, it indicates that there is inflammation in the body, which is mostly considered to be inflammation of the lungs and inflammatory nodules, etc. If the cytology is malignant, then corresponding surgical treatments or radiotherapy will be adopted. To summarize, if the patient appears to have nodular high-density shadow in chest X-ray, he should go to the hospital in time to improve the relevant examination, to clarify the cause of the disease, and target treatment.