Medication changes are usually done about three days after lipoma surgery, depending on the condition of the wound. Lipoma a benign tumor, can be single, multiple in different parts of the body. Lipoma excision is a clean wound, and the medicine should be changed regularly after the surgery. The medicine is usually changed around the third day after the surgery. When changing the medicine, you should pay attention to whether the wound has symptoms such as redness, swelling, burning, pain, etc. If these symptoms occur, the wound may have inflammation and infection, and you should carry out anti-infection treatment in time, for example, use amoxicillin, roxithromycin and other drugs under the guidance of the doctor. After the surgery, it is recommended to take more rest and eat more fresh fruits and vegetables to ensure a healthy and comprehensive diet. You should also keep a good state of mind and change medication and review regularly.