Keratosis pilaris on both sides of the foot may be caused by tinea pedis, chronic eczema or palmoplantar keratosis, it is recommended that the patient under the guidance of a doctor to clarify the specific cause of the disease and then symptomatic treatment: 1. Tinea pedis: Tinea pedis is caused by fungal infections, especially scaly keratosis pilaris, which can be manifested as thickening of the skin on both sides of the foot and keratinization of the phenomenon. Patients can use topical terbinafine cream and other antifungal drugs, and at the same time, topical salicylic acid ointment and other softening of the skin lesions, for improvement. 2. Chronic eczema: chronic eczema is mostly developed from acute eczema, which can be manifested as thickened skin keratinization on both sides of the foot. Patients can use topical halometasone cream, florazepam cream to improve the symptoms. 3. Palmoplantar keratosis: palmoplantar keratosis is characterized by excessive keratinization and thickening of the skin of the hands and feet. Treatment can be topical urea ointment, retinoic acid cream or salicylic acid ointment to improve the symptoms. When patients have keratosis on both sides of the feet, it is recommended that they go to regular hospitals for timely examination and standardized treatment under the guidance of professional doctors.