Cholesteatoma surgery usually costs around $200 to $30,000. Often cholesteatomas, also known as epidermoid cysts, can be present inside the skull and in the middle ear drum chamber. If the cholesteatoma is present within the skull, it can be treated with either craniotomy or transsphenoidal sinus neuroendoscopic surgery. The average cost of craniotomy is about $20,000 and transsphenoidal sinus neuroendoscopic surgery is about $30,000. And the middle ear tympanic chamber can be divided into outer ear cholesteatoma and middle ear cholesteatoma. In case of outer ear cholesteatoma, the cost of surgery is usually $200 and in case of middle ear cholesteatoma, the cost of surgery is usually around $12,000. Therefore, the cost of cholesteatoma surgery needs to be determined on a patient-by-patient basis. Patients are advised to seek prompt medical attention if they experience discomfort to avoid delays.