”Thank you so much to Professor He and the urologists at the Third Xiangya Hospital! You have given me a second life!” A patient with bladder cancer who underwent surgery to remove and reconstruct his bladder a year ago made a heartfelt statement. Recently, doctors confirmed that the patient’s bladder cancer has been cured and all physiological indicators are normal, thus also completely shaking off the burden of having to live with a urine bag for life after the previous surgery. A year ago, 32-year-old Ms. Chen came to our hospital due to recurrent painless hematuria and returned to Hunan from Guangdong. After ultrasound, CT scan, cystoscopy and biopsy, she was diagnosed with “multiple bladder cancer” and her bladder was filled with no less than 15 large and small masses, which required “total bladder surgery”. According to the previous surgical method, “urinary diversion” is required after total cystectomy. A urinary diversion is a procedure in which urine is passed through a stoma in the abdominal wall and the patient is required to self-catheterize from the abdomen at regular intervals or wear a urinary bag for life to drain urine. As the skin around the stoma is prone to complications such as inflammation and ulceration, the stoma is also prone to stenosis leading to fluid accumulation in the kidneys and impaired function; sometimes the urine bag is accidentally dropped, leading to “water flooding”, and the wet clothes and pants and their odor will not only make the patient frustrated and unhappy, but will also be in a very embarrassing situation from time to time, seriously affecting The patient’s social activities and physical and mental health are seriously affected. In view of this, Professor He Le Ye, the head of the Department of Urology, immediately worked with the whole department and decided to perform a “total bladder excision and in situ ileal neo-bladder reconstruction surgery”, i.e., to use a 40 cm long section of the patient’s own ileum to make a “urinary bladder”, forming a bladder that is physiologically and anatomically similar to a normal bladder. The new bladder is then anastomosed to the urethra and bilateral ureters respectively. The new bladder was then anastomosed with the urethra and bilateral ureter respectively. After the operation, the patient could not only control urination through the normal urethra without wearing a urinary bag, but also restored the ability of urine storage and urination to the maximum extent, while the tumor lesion was completely removed, achieving the goal of complete treatment. With the successful implementation of this new procedure, Ms. Chen has now returned to her previous state of free and easy living. It is reported that this surgical approach is at the forefront of the peers in the province.