Liver-stomach disharmony (disharmony between the ascending function of the liver and the descending function of the stomach and internal organs) is mainly classified as liver qi offending the stomach (the liver qi is not smooth and affects the function of the stomach), and deficiency and cold in the middle jiao, etc. Mental depression, impatience, and distension and pain in the middle and upper abdomen are the main clinical manifestations. Liver qi offending the stomach is treated with Chai Hu Shu Hepatosan and Zuo Jin Wan plus or minus; cold invading the liver and stomach is treated with Xiao Jian Zhong Tang plus or minus. Patients with liver-qi attacking the stomach mainly manifest pain and distension in the stomach and epigastric region, eructation (hiccup), vomiting, irritability and acid reflux, and such patients can follow the doctor’s instruction to use Chaihu Shunhe San and Zuojin Wan plus or minus for treatment. Patients with deficiency and cold in the middle jiao mainly show symptoms such as pain in the abdomen (spasm and convulsion of the body due to wind-cold sensation), fond of warmth and pressure, fatigue (mental exhaustion and physical weakness), and deficiency and timidity, etc. Such patients can be treated by adding or subtracting Xiao-Jian-Zhong Tang as prescribed by the doctor. If the liver and stomach are not in harmony, the patient should consult a doctor in time. The above mentioned Chinese medicines are recommended to be used under the guidance of a traditional Chinese medicine practitioner, as unauthorized use of these medicines may lead to serious consequences.