The relationship between a sore throat and thyroid nodules is generally small, but if the thyroid nodules are large enough to compress the airways, it is possible to cause a sore throat. Thyroid nodules in most cases do not have any clinical manifestations, only found during physical examination, some patients may have neck pain, throat discomfort, difficulty in swallowing, etc. If there is a significant enlargement, compression of the trachea, which can lead to a sore throat, but it is generally less common. Sore throat is mostly caused by external stimulation, infection and other factors, the common reason for eating spicy and stimulating food leads to throat irritation, various pathogenic bacteria infection, such as pharyngitis, tonsillitis and other factors lead to. In conclusion, if you have a sore throat or thyroid nodules, you should go to the hospital in time and be treated under the guidance of your doctor.