Pantoprazole sodium enteric-coated tablets and aspirin can be used together. Pantoprazole sodium enteric-coated tablets belong to proton pump inhibitors, a kind of drug that inhibits gastric acid secretion and protects the gastric mucosa. Clinical applications occasionally have adverse reactions such as dizziness, insomnia, somnolence, nausea, abdominal pain, diarrhea and constipation, abdominal distension, skin rash, muscle pain. It is contraindicated in lactating women and women in the third trimester of pregnancy; it is contraindicated in those who are allergic to the product. Aspirin belongs to the non-steroidal anti-inflammatory drugs, can inhibit the enzyme cyclo-oxygenase, has the effect of anti-platelet aggregation, is now mostly used to prevent the formation of blood clots. Taking aspirin may have the risk of bleeding, should not be used with anticoagulant drugs; people with asthma should not take. Taking aspirin can damage the gastric mucosa, long-term use can cause gastric ulcers and gastric bleeding. The two used together can protect the gastric mucosa, relieve gastrointestinal discomfort, and prevent peptic ulcers, gastrointestinal bleeding and other events. Pantoprazole sodium enteric-coated tablets with aspirin need to be used under the guidance of a professional doctor, avoid self-medication.